杨立荣
职称：教授
学位：生物化工博士
出生年月：1962年8月
电话&传真：0571-87952363
Email：lryang@zju.edu.cn
地址：浙江大学（玉泉校区）材料与化工学院生物工程研究所，杭州，310027
研究方向: 生物催化与转化、酶工程、生物过程工程。
Dr. Li-rong Yang Ph.D.
Professor, Institute of Bioeng.
Dept. of Chem. Eng. & Bioeng.
College of Materials Science and Chemical Engineering
Zhejiang University, Hangzhou 310027 China
Tel:86-571-87952363
Fax:86-571-87952363
E-mail: lryang@zju.edu.cn
Education Background
Ph. D., Dept. Of Chem. Eng. & Biochem. Eng., Zhejiang University(2003), Majored in Biochem. Eng.
M.S., Dept. of Chem. Eng., Zhejiang University(1991), Majored in Biochem. Eng.
B.Sc., Dept. of Chem. Eng., Zhejiang University of Technology(1984), Majored in Fine Chem. Eng.
Working Experience:
12/2002- Present ?Dept. of Chem. Eng., Zhejiang University
Position: Professor ?Field: Biochem. Eng. & Applied Chemistry
10/1997-11/2002 ?Dept. of Chem. Eng., Zhejiang University
Position: Associate Professor Field: Biochem. Eng. & Applied Chemistry
3/1993-9/1997 Dept. of Chem. Eng., Zhejiang University
Position: Lecturer ?Field: Biochem. Eng. & Applied Chemistry
1/1991-3/1993 Dept. of Light Industry Eng., Zhejiang University of Technology
Position: Lecturer Field: Biochem. Eng. & Fermentation Eng.
8/1984-12/1990 ?Dept. of Chem. Eng., Zhejiang University of Technology
Position: Assistant Field: Fine Chem. Eng. & Applied Chemistry
Teaching:
Biocatalysis and Biotransformation
Introduction to Bio-engineering
Research Interests & Current Projects
Research Interests:
iochem. Eng., Biocatlysis & Biotransformation, Enzyme Eng., Applied Chemistry. Specially focus on Chiral Drugs & Chiral intermediates; Enzyme in non-conventional media; Peptide Synthesis.
工作研究领域
生物催化与转化、酶工程、生物过程工程。
工作研究项目
Ｄ－泛硫乙胺的分离与纯化技术开发
杭州鑫富药业股份有限公司 20070531
离子液体中全细胞体系不对称还原潜手性羰基的研究
国家自然科学基金委 20081231
S-西酞普兰的化学－酶法制备技术的研究
浙江省科技厅 20081231
三唑类农药杀菌剂
江苏丰登农药有限公司 20080627
西酞普兰中间体的酶拆分技术
浙江华海药业股份有限公司 20081231
浙大上峰化工研究中心
海宁上峰化工有限公司 20080631
新型生物催化剂的研制及应用基础研究
自选课题 国家自然科学基金委员会 20071231
S-a-氰基-3-苯氧基苄醇及相关生物菊酯的开发
中国科学技术部 20051031
含氰生物菊酯的研究开发
常州康美化工有限公司 20081231
医药中间体开发联合实验室
海宁市上峰化工有限公司 20060601
生物催化和生物转化中关键问题的基础研究
中华人民共和国科学技术部 20071231
含氰基手性中间体及相关菊脂的研究
20041221
生物菊酯手性中间体
20031201
生物和化学协同催化不对称合成方法的基础和工程研究
20011231
研究成果
Kinetics of Butyl Acetate Synthesis by Lipase-Cata
Immobilization of lipase on the salts and its catalytic activity
KINETICS OF BUTYL ACETATE SYNTHESIS BY LIPASE-CATA
Lipase-catalyzed alcoholysis of alpha-cyano-3-phenoxybenzyl acetate in organic media
Preparation of (R)-ethyl 4-chloro-3-hydroxybutanoate through enzymatic ammonolysis in organic media
Asymmetric reduction of o-chloroacetophenone with Candida pseudotropicalis 104
Separation of alpha-cyano-3-phenoxybenzyl alcohol from alpha-cyano-3-phenoxybenzyl acetate using solvent extraction
Efficient lipase-catalyzed kinetic resolution of 4-arylmethoxy-3-hydroxybutanenitriles: application to an expedient synthesis of a statin intermediate
2006-11-25
有机相酶催化氨解反应拆分制备(R)-4-氯-3-羟基丁酸乙酯
2006-10-25
Separation of α-cyano-3-phenoxybenzyl alcohol fromα-cyano-3-phenoxybenzyl acetate using solvent extraction
2006-10-25
手性芳香胺的酶法拆分
2006-10-20
Asymmetric Reduction of o-Chloroacetophenone with Candida pseudotropicalis 104
2006-09-15
3-氯-1-(2-噻吩)-丙酮合成工艺的研究
2006-04-25
相转移催化法合成2-氯-3-氯甲基-噻吩及噻康唑
2006-01-12
金属氯化物对硼氢化钠还原α-氯代苯乙酮的影响
2006-01-06
金属氯化物对硼氢化钠还原a-氯代苯乙酮的影响
2005-12-01
酶催化氨解反应拆分4-氯-3-羟基丁酸乙酯
2005-11-01
苯醚氰醇与苯醚氰醇乙酸酯的液－液萃取分离
2005-11-01
α-苯乙氰醇与α-苯乙氰醇乙酸酯萃取分离过程的研究
2005-11-01
Enzymatic ammonolysis of ethyl 4-chloro-3-hydroxybutanoate in organic solvents
2005-10-01
The Separation of Mandelonitrile and Mandelonitrile Acetate by Solvent Extraction
2005-10-01
Kinetic Resolution of 1-(2,4-dichlorophenyl)-2-chloro-ethanol and
2005-10-01
1-(2,4-difluorophenyl)-2-chloro-ethanol by Lipase-catalyzed Irreversible Transesterification
2005-10-01
The Kinetic Resolution of HMPC Acetate by Lipase-catalyzed Alcoholysis in Organic Media
2005-10-01
The lipase-catalyzed enantioselective transesterification of mandelonitrile in organic media
2005-10-01
有机介质中脂肪酶催化转酯化反应拆分苯乙氰醇的研究
2005-08-01
硼氢化钠还原法合成1-(2,4-二氯苯基)-2-氯-乙醇
2005-06-01
离子液体及其在生物催化中的应用
2005-04-01
Optimization of technological conditions for one-pot synthesis of S-a-cyano-3-phenoxybenzyl acetate in organic media
2005-03-01
脂肪酶固定化研究和应用
2005-02-01
Determination of internal diffusion limitation and its macroscopic kinetics of the transesterification of CPB alcohol catalyzed by immobilized lipase in organic media
2005-02-01
2’,4-二氯苯乙酮的合成研究
2004-12-01
双水相分配技术的基础及工程研究
一等,1998-01-01
双水相分配技术的基础及工程研究
一等,1997-01-01
